Prediction Sheet 1 — High-Yield Topic Pool

100Topics

17Seen in all 5 papers

55Seen in 3+ papers

94/100Matched to papers

14Subjects

Evidence 3+ papers2 papers 1 paperPrediction onlyNot in past papers

	Topic	Evidence	Seen in	TriggerRecognition trigger	Key discriminator	Main trap
1	Aortic dissection	Dec25 only	Jun24Dec24Jun25Dec25May26	Sudden tearing chest/back pain + BP difference between arms	CT angiography for diagnosis; Type A surgery, Type B IV beta-blocker	Treating as MI based on chest pain alone
3	Rheumatoid arthritis	Seen in 4 of 5 papers	Jun24Dec24Jun25Dec25May26	Symmetric MCP/PIP pain + morning stiffness >1 hour	Anti-CCP is the best confirming test when asked	Mistaking shoulder pain or age for OA
4	Osteoarthritis	Seen in 4 of 5 papers	Jun24Dec24Jun25Dec25May26	Elderly + DIP Heberden nodes + pain worse with use	DIP involvement strongly favors OA	Confusing PIP Bouchard nodes with RA
6	IgA nephropathy	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Hematuria during or immediately after URTI	Synpharyngitic hematuria, often normal C3	Post-strep GN timing
13	Esophageal varices	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Cirrhosis/portal HTN + hematemesis	Endoscopic band ligation; vasoactive bridge may be terlipressin/octreotide	Mallory-Weiss or PPI-only answer
14	H. pylori eradication confirmation	May26 only	Jun24Dec24Jun25Dec25May26	Treated PUD after triple therapy	Urea breath test for eradication	Serology, endoscopy, barium
15	IBS	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Chronic abdominal pain relieved by defecation + normal workup	No red flags; stress worsens	IBD when there is no blood/weight loss
16	Chronic bronchitis	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Smoker + productive cough for 2 years	Productive cough >=3 months/year for 2 years	Asthma or bronchiectasis
17	Pleural effusion vs collapse	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Dullness with tracheal shift	Effusion pushes trachea away; collapse pulls toward	Pneumothorax if percussion note ignored
18	Goodpasture syndrome	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Hemoptysis + hematuria/RBC casts	Anti-GBM pulmonary-renal syndrome	GPA/Wegener without ENT/sinus clue
19	Cushing syndrome	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Purple striae + proximal weakness + HTN + eosinopenia	Cortisol excess	Addison, hypothyroid, diabetes
20	Hypocalcaemia	Dec25 only	Jun24Dec24Jun25Dec25May26	Tetany + Chvostek/Trousseau	Low calcium	Magnesium or potassium reflex answer
21	Hyperparathyroidism	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Bone/renal symptoms or early biochemical clue	Early hypophosphatemia; later hypercalcemia	Choosing PTH/hypercalcemia for earliest abnormality
22	Parkinson disease	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Resting tremor + rigidity + bradykinesia + shuffling gait	Resting tremor; substantia nigra dopamine loss	Essential tremor/intention tremor
23	Myasthenia gravis	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Ptosis/diplopia worse at day end, improves with rest	Pyridostigmine for symptomatic treatment	GBS or Lambert-Eaton
24	Guillain-Barre syndrome	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Ascending weakness after infection + areflexia	Acute inflammatory demyelinating polyneuropathy	Myasthenia or MS
25	Amaurosis fugax / TIA	Prediction only	—	Transient monocular blindness	Retinal artery embolic TIA	Treating as completed stroke only
26	AML	May26 only	Jun24Dec24Jun25Dec25May26	Auer rods + MPO positive +/- gum hyperplasia	Auer rods = AML	ALL because of blasts
27	CML	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Massive splenomegaly + myeloid left shift	BCR-ABL / Philadelphia chromosome	CLL or myelofibrosis
28	Iron deficiency anemia	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Microcytic hypochromic anemia + low ferritin	Low ferritin + high TIBC	Thalassemia trait
29	B12 deficiency	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Macrocytosis + glossitis + posterior column signs	Pernicious anemia if Schilling/intrinsic factor clue	Folate deficiency
30	Gout	Seen in 4 of 5 papers	Jun24Dec24Jun25Dec25May26	Sudden painful red first MTP	Podagra	RA/OA
91	Doubling time	Dec25 only	Jun24Dec24Jun25Dec25May26	Population growth rate given	Rule of 70	Exact arithmetic trap
92	Study design	Syllabus core	—	Groups receive surgery vs diet/intervention	Randomized controlled trial if assigned intervention	Cohort because groups are followed
93	Data presentation	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Percentages/proportions asked	Pie chart	Bar chart when parts of whole
94	Median/biostatistics basics	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Skewed data or middle value	Median	Mean

	Topic	Evidence	Seen in	TriggerRecognition trigger	Key discriminator	Main trap
9	Testicular torsion	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Sudden severe testicular pain + high-riding testis + absent cremasteric reflex	Urgent surgical exploration if Doppler unavailable	Waiting for imaging
10	Perforated peptic ulcer	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Sudden severe abdominal pain + board-like rigidity + free air	Exploratory laparotomy / surgical management	PPI or endoscopy as definitive step
11	Esophageal carcinoma	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Progressive dysphagia solids first then liquids + weight loss	Mechanical obstruction pattern	Achalasia
12	Achalasia	Seen in 4 of 5 papers	Jun24Dec24Jun25Dec25May26	Dysphagia to liquids and solids + bird-beak	Functional obstruction; manometry/endoscopy depending wording	Cancer when liquids are involved early
41	Femoral hernia location	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Groin swelling below pubic tubercle	Below and lateral to pubic tubercle	Inguinal hernia locations
42	Direct inguinal hernia	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Hernia through Hesselbach triangle	Direct inguinal	Indirect hernia
43	Thyroglossal duct cyst	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Midline neck swelling moves with tongue protrusion	Thyroglossal duct cyst	Thyroid nodule/branchial cyst
44	Breast carcinoma severity/workup	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Hard irregular lump, skin changes, nodes	Triple assessment; lymph nodes worsen prognosis	Fibroadenoma/reassurance
45	Fibroadenoma	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Young woman + painless mobile breast lump	Reassurance/follow-up if classic small lesion	Mastectomy/cancer management
46	Intraductal papilloma	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Bloody nipple discharge from single duct, no lump	Intraductal papilloma	Breast carcinoma
47	Acute appendicitis	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Periumbilical pain migrates to RIF + rebound	Appendectomy/definitive surgical management	Antibiotics only
48	Tension pneumothorax	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Hypotension + tracheal deviation + absent breath sounds	Needle decompression before CXR	Waiting for imaging
49	Burns escharotomy	Jun25 only	Jun24Dec24Jun25Dec25May26	Circumferential burn + weak pulses + paresthesia	Escharotomy	Fasciotomy or fluids only
50	Pelvic fracture shock	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Pelvic fracture + shock	Internal hemorrhage/blood loss	Fat embolism/head injury
51	Gallstone disease / cholangitis	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	RUQ pain + fever + jaundice + CBD stone	Urgent ERCP if septic cholangitis	Cholecystectomy first
52	Pancreatic pseudocyst	Dec25 only	Jun24Dec24Jun25Dec25May26	Epigastric mass 4-6 weeks after pancreatitis	Pseudocyst without fever	Abscess/cancer

	Topic	Evidence	Seen in	TriggerRecognition trigger	Key discriminator	Main trap
5	Post-streptococcal GN	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Cola urine + periorbital edema 1-3 weeks after sore throat	Latent period after infection + low C3	IgA nephropathy, which occurs during URTI
7	Epiglottitis	Seen in 4 of 5 papers	Jun24Dec24Jun25Dec25May26	Toxic child + drooling + tripod + thumb sign	Secure airway first in controlled setting	Examining throat or delaying for imaging
63	Down syndrome	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Upslanting eyes + single palmar crease	Trisomy 21; VSD/AV canal associations	Patau/Edwards
64	Erb palsy	Seen in 4 of 5 papers	Jun24Dec24Jun25Dec25May26	Newborn after difficult delivery + waiter's tip	C5-C6 upper trunk	Klumpke palsy
65	Severe dehydration	Seen in 4 of 5 papers	Jun24Dec24Jun25Dec25May26	Drowsy child with profuse diarrhea/vomiting unable to drink	IV Ringer lactate	ORS when severe
66	Neonatal CPR ratio	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Newborn resuscitation compression:ventilation	3:1	Adult/pediatric ratios
67	Vitamin K deficiency bleeding	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Newborn bleeding, no prophylaxis	Vitamin K deficiency	Hemophilia
68	Rickets	May26 only	Jun24Dec24Jun25Dec25May26	Bowed legs + rachitic rosary + low Ca/phosphate + high ALP	Vitamin D deficiency	Renal failure/excess calcium
69	Croup	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Barking cough + steeple sign + non-toxic	Nebulized adrenaline/steroids depending severity	Epiglottitis
70	Autism	Dec25 only	Jun24Dec24Jun25Dec25May26	Poor eye contact + hand flapping + delayed speech	Autism spectrum disorder	CP/ADHD

	Topic	Evidence	Seen in	TriggerRecognition trigger	Key discriminator	Main trap
2	Anti-D immunoglobulin	Seen in 4 of 5 papers	Jun24Dec24Jun25Dec25May26	Rh-negative mother + Rh-positive baby or sensitising event	Give anti-D within 72 hours	Choosing 24h/48h/96h instead of 72h
53	Placenta previa	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Painless bright red antepartum bleeding + soft uterus	Avoid PV exam until placenta location known; CS if major/late	Abruption
54	Placental abruption	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Painful bleeding + tender rigid uterus + fetal distress	Pain and uterine tenderness	Placenta previa
55	Ectopic pregnancy	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Amenorrhea + abdominal pain + bleeding + shock	Rule out first in reproductive-age acute abdomen	PID/miscarriage without pregnancy test
56	Severe pre-eclampsia / HELLP	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	BP >=160/110 + proteinuria + headache/epigastric pain +/- low platelets	MgSO4 for seizure prophylaxis; delivery depending gestation/stability	Simple gestational HTN
57	Gestational diabetes	Seen in 4 of 5 papers	Jun24Dec24Jun25Dec25May26	Pregnancy 24-28 weeks / glucosuria	OGTT	Random glucose/urine glucose
58	Preterm labor steroids/neuroprotection	Dec25 only	Jun24Dec24Jun25Dec25May26	Preterm contractions with cervical dilation	Betamethasone for lung maturity; MgSO4 for neuroprotection if very preterm	Continuing tocolysis as fetal outcome drug

	Topic	Evidence	Seen in	TriggerRecognition trigger	Key discriminator	Main trap
59	PCOS	Jun24 only	Jun24Dec24Jun25Dec25May26	Infertility + obesity + hirsutism + irregular cycles	Hyperandrogenism + polycystic ovaries	Endometriosis/hyperprolactinemia
60	Androgen insensitivity	Syllabus core	—	Primary amenorrhea + blind vagina + absent uterus + 46XY + normal breasts	Testicular feminization/AIS	Mullerian agenesis if karyotype is 46XX
61	Abnormal uterine bleeding in adolescence	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Heavy bleeding since menarche, pregnancy/coag normal	Anovulatory cycles most common	Fibroid/cancer
62	GTN	Syllabus core	—	High beta-hCG + bleeding after pregnancy/molar features	Serial beta-hCG follow-up	Normal miscarriage follow-up

	Topic	Evidence	Seen in	TriggerRecognition trigger	Key discriminator	Main trap
8	Nasal foreign body	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Child + unilateral foul-smelling/blood-stained nasal discharge	Foreign body until proven otherwise	Treating as sinusitis
98	Otic barotrauma	Dec25 only	Jun24Dec24Jun25Dec25May26	Ear pain/fullness after airplane travel + retracted congested TM	Barotrauma	AOM/cholesteatoma
99	Retropharyngeal abscess	Dec25 only	Jun24Dec24Jun25Dec25May26	Child + fever + neck stiffness + pharyngeal abscess	Retropharyngeal space	Submandibular/parapharyngeal

	Topic	Evidence	Seen in	TriggerRecognition trigger	Key discriminator	Main trap
71	Acute angle-closure glaucoma	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Painful red eye + halos + fixed mid-dilated pupil	Lower IOP urgently; pilocarpine may appear after pressure lowered	Conjunctivitis
72	Vernal keratoconjunctivitis	Dec25 only	Jun24Dec24Jun25Dec25May26	Child + severe itching in summer + cobblestone papillae	Spring catarrh	Bacterial/viral conjunctivitis
73	Endophthalmitis	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Severe pain/redness/hypopyon 1 day after cataract surgery	Post-op endophthalmitis	Lens reaction
74	Amblyopia from strabismus	Dec24 only	Jun24Dec24Jun25Dec25May26	Child with long-standing squint + reduced vision, normal structures	Amblyopia	Cataract/glaucoma

	Topic	Evidence	Seen in	TriggerRecognition trigger	Key discriminator	Main trap
95	Kerosene ingestion	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Child ingests kerosene	Aspiration pneumonitis/bronchopneumonia	Gastric lavage/toxicity focus
96	Rigor mortis timing	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Rigor distribution after death	Estimate PMI from progression	Treating rigor as instant
97	Organophosphate poisoning	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Salivation, lacrimation, bronchorrhea, miosis	Atropine + pralidoxime	Naloxone/benzodiazepine

	Topic	Evidence	Seen in	TriggerRecognition trigger	Key discriminator	Main trap
35	Warfarin reversal	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Warfarin + high INR +/- bleeding	Oral vitamin K for high INR/no major bleed; PCC/FFP if major bleed	Protamine
36	Paracetamol overdose	Dec25 only	Jun24Dec24Jun25Dec25May26	Child ingests paracetamol	N-acetylcysteine if toxic risk/level	Observation when risk remains unclear
37	Benzodiazepine antidote	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Sedation + normal pupils + ataxia	Flumazenil	Naloxone
38	Phenytoin adverse effects	Seen in 4 of 5 papers	Jun24Dec24Jun25Dec25May26	Gingival hyperplasia + hirsutism	Phenytoin signature	Carbamazepine/valproate
39	Wernicke encephalopathy	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Alcoholic + confusion + ataxia + ophthalmoplegia	Thiamine before glucose	Giving glucose first
40	ACE inhibitor in diabetic nephropathy	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	DM + HTN + microalbuminuria/proteinuria	ACEi/ARB renal protection	CCB/thiazide as generic HTN answer

	Topic	Evidence	Seen in	TriggerRecognition trigger	Key discriminator	Main trap
81	Hypersensitivity types	Seen in 4 of 5 papers	Jun24Dec24Jun25Dec25May26	Asked to classify TB, PSGN, AIHA, contact dermatitis	I, II, III, IV examples cold	Type III vs IV
82	Barrett esophagus	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Chronic GERD + squamous to columnar change	Metaplasia, premalignant	Dysplasia/hyperplasia
83	Acute inflammation mediator	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Immediate vascular permeability	Histamine	Prostaglandins/cytokines
84	Marjolin ulcer	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Chronic burn scar ulcer becomes raised non-healing nodule	SCC in scar; wide local excision	Venous/diabetic ulcer
85	TTP vs DIC	Dec25 only	Jun24Dec24Jun25Dec25May26	MAHA + thrombocytopenia; coag profile asked	TTP normal PT/APTT; DIC prolonged	Treating all MAHA as DIC

	Topic	Evidence	Seen in	TriggerRecognition trigger	Key discriminator	Main trap
75	Common peroneal nerve	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Fibular neck injury + foot drop	Common peroneal nerve	Sciatic nerve
76	Radial nerve	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Midshaft humerus fracture + wrist drop	Radial nerve	Axillary nerve
77	Axillary nerve	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Surgical neck humerus + deltoid weakness + regimental badge numbness	Axillary nerve	Radial nerve
78	Anterior interosseous nerve	Prediction only	—	Supracondylar fracture + cannot make OK sign	AIN branch of median nerve	Ulnar or radial nerve
79	Facial nerve lesion level	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Facial palsy + hyperacusis	Lesion proximal to nerve to stapedius	Stylomastoid foramen lesion
80	Brainstem crossed syndrome	Dec25 only	Jun24Dec24Jun25Dec25May26	Ipsilateral cranial nerve palsy + contralateral hemiplegia	Brainstem lesion	Internal capsule/cortex

	Topic	Evidence	Seen in	TriggerRecognition trigger	Key discriminator	Main trap
86	Metabolic alkalosis from vomiting	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Vomiting + high pH + high HCO3 + low Cl	Metabolic alkalosis	Respiratory alkalosis
87	High altitude response	Syllabus core	—	Shift to high altitude	Hyperventilation lowers pCO2	Assuming CO2 rises
88	Pancreatic bicarbonate secretion	Seen in 4 of 5 papers	Jun24Dec24Jun25Dec25May26	High flow pancreatic secretion	HCO3-rich ductal secretion	Chloride
89	Resting membrane/action potential ions	Seen in 4 of 5 papers	Jun24Dec24Jun25Dec25May26	Resting potential/depolarization asked	Resting = K; depolarization = Na influx	Mixing phases
90	Shock hemodynamics	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Compare anaphylactic/hypovolemic/cardiogenic shock	Anaphylaxis low SVR; cardiogenic low CO	Treating all shock as low CO

	Topic	Evidence	Seen in	TriggerRecognition trigger	Key discriminator	Main trap
31	CAP organism	Seen in 5 of 5 papers	Jun24Dec24Jun25Dec25May26	Most common CAP organism	Streptococcus pneumoniae	H. influenzae as second common
32	Meningitis investigation	Seen in 3 papers	Jun24Dec24Jun25Dec25May26	Fever + neck stiffness/bulging fontanelle	Lumbar puncture if no raised ICP contraindication	Blood CP/culture as confirmation
33	ATT adverse effects	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	ATT + joint pains/hyperuricemia	Pyrazinamide	INH or rifampicin
34	Measles	Seen in 4 of 5 papers	Jun24Dec24Jun25Dec25May26	Fever + cough/coryza/conjunctivitis + Koplik spots	Koplik spots	Rubella/scarlet fever

	Topic	Evidence	Seen in	TriggerRecognition trigger	Key discriminator	Main trap
100	Psoriasis	Seen in 2 papers	Jun24Dec24Jun25Dec25May26	Extensor plaques + silvery scales + nail pitting	Psoriasis	Tinea/eczema